In reply:PICO questions in systematic reviews.

Dear Editor, We would like to thank Amir-Behghadami and Janati for sharing their thoughts and comments on our systematic review.1 They emphasise that formulating a PICO question aids in optimising the structure of a systematic review. We think it is important to adhere to the PRISMA guidelines for performing a systematic review. In the PRISMA statement, it is advised that a structured approach should be used in order to facilitate the …