Chapter 2 – Novel Therapies for Multiple Sclerosis: A Mechanistic View

Multiple sclerosis (MS) is presumed to be an autoimmune disease of human brain and spinal cord which mainly affects young adults. MS pathophysiology contains two neuroinflammatory and neurodegenerative arms which run concurrently; however, it is the neurodegeneration that eventually leads to loss of neurons and axons and permanent disability. Presently, MS remains incurable and we present a mechanistic review of the present and emerging therapies for this fascinating disease.