Chemical Constituents from Centaurea parviflora Desf.

Phytochemical investigation of the aerial parts of Centaurea parviflora Desf. led to the isolation of 13 secondary metabolites : 5-hydroxy-6,7,3’,4’-tetramethoxyflavone (1), eupatilin (2), eupatorin (3), cirsilineol (4), jaceosidin (5), 5Hα,6Hβ,7Hα-15-hydroxy-8α-(1’,2’-dihydroxyethyl-acryloxy)-elema-1(2),3(4),11(13)-trien6,12-olide (6), genkwanin (7), thevetiaflavone (8), cnicin (9), ethyl-O-L-arabinofuranoside (10), cornicinine (11), syringin (12) and nicotiflorin (13).The structures were established by the combination of their spectroscopic data, notably the analysis of UV, 1 H, 13 C NMR, DEPT, HSQC, NOESY, HMBC spectra as well as by HRESI-MS. All these compounds were described for the first time from this species. Compound (11) is new for all the reign plant, while compound 10 is new for the genus Centaurea.