In Vitro Bactericidal Activity of Jinghua Weikang Capsule(荆花胃康胶丸)and Its Individual Herb Chenopodium Ambrosioides L.against Antibiotic-Resistant Helicobacter Pylori

Objective:To investigate the bactericidal effects of Jinghua Weikang Capsule(荆花胃良胶丸and its major component Chenopodium ambrosioides L.on antibiotic-resistant Helicobacter pylori.Methods: Four clinical antibiotic-resistant H.pylori strains were isolated and incubated in liquid medium containing Jinghua Weikang Capsule or Chenopodium ambrosioides L By means of time-kill curve method,the average colony counts and bactericidal rate were calculated at time points of 0,4,8 and 24 h after the incubation and the time-kill curves were charted.Results:Both Jinghua Weikang Capsule and Chenopodium ambrosioides L at a concentration of 0.64 g/L showed obvious bactericidal effect against antibiotic-resistant H.pylori after 4 h of incubation.Conclusion:Jinghua Weikang Capsule and Chenopodium ambrosioides L.are considered to be active against antibiotic-resistant H.pylori in vitro.