Histiocitosis de células de Langerhans con manifestaciones multisistémicas en periodo neonatal

We report an unusual case of mediastinal abcessed mass, with involvement of the lung, thymus and probably bone and hematopoietic system, in a newborn that was diagnosed with Langerhans cell histiocytosis. Its interest lies in the presentation as a rare cause of medias­tinal mass with involvement of other organs. Histologic exa­mination of the surgical specimen demonstrated Langerhans cell histiocytosis. It is known that vascular and lymphatic malformations, with teratomas, neurogenic tumors, lympha­denopathy of infectious origin and mediastinitis, are a major cause of mediastinal masses; in this case, it must also take into account the Langerhans Cell Histiocytosis as a cause. It had already reported cases of congenital solid masses neck and thigh as a unique presentation of this disease.