Etude comparative de la séroprévalence des infections au VIH, VHB ET VHC chez les donneurs de sang en collecte fixe et mobile

2019 
Objective: The objective was to compare the seroprevalence of human immunodeficiency virus (HIV) and hepatitis B and C (HBV and HCV) viruses among blood donors seen in mobile and fixed booths at the National Blood Transfusion Center in Bamako. Patients and methods: This was a cross-sectional prospective study that took place over 15 months in Bamako and around. A total of 6,600 donors, including 3,300 for each type of collection (mobile and fixed), were included according to their ability to donate blood. Blood samples were tested by ELISA. The data entered on EPI INFO 7.0 was analyzed on SPSS 20.0. The χ2 test was used to compare proportions with a meaningful threshold of 0.05. The study was carried out in accordance with the ethical rules related to research on human subjects. Results: The sex ratio was 4.96 and the average age was 30.03 ± 9.04 years. Prevalence of HIV, HBV and HCV were 2%, 18.1% and 3%, respectively, among all donors. Male and age group [18 - 25] were significantly affected by HBV. HIV prevalence was significantly higher in mobile collection (2.5%) than in fixed centers (1.5%), p=0.003. HBV and HCV prevalence were equal for both collections, with 18.2% and 3% for mobile booth and 18% and 3% for fixed ones. Coinfections were more common in mobile collection than in fixed ones. Conclusion: HIV prevalence was high in mobile rather than fixed collection. There was no difference in prevalence of HBV and HCV between the two types of collections. In order to cover transfusion needs in quantity and quality, a strategy adjustment seems more than necessary. This new approach must focus on customizing donors seen in both fixed and mobile booths, free of infections transmitted by transfusion.
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