Registro, clasificación y estudio de imágenes digitalizadas de resonancia magnética del cerebro humano (...) como complemento al estudio de modificaciones cerebrales relacionadas a la edad, el sexo y/o patología

2017 
Angle values measured in images, including magnetic resonance imaging of the brain, are independent of image size. This property would determine, in both sexes, changes with age and eventually the pathology of brain areas involved. When an angle varies significantly in any of the above conditions suggests that compromises the form modification .Because each angle is plotted between reliable anatomic landmarks, identifiable in eachimage, a significant variation in the angle measure is indicative of variation of the position of the anatomic landmarks in the brain imaging surface and, therefore, the brain area that includes them. Consequently, a significant variation of angles relative to normal limits by sex and age could provide relevant information for diagnosis of diseases. One objective of this project was to determine the value of two angles corresponding to the image of the parietal lobe of both hemispheres at the same age in both sexes. Using the program Scion Image for Windows in parasagittal MRIs of 65 subjects without psychiatric or neurological disease, of both sexes and between 41 and 60 years, they were drawn in each hemisphere two adjacent angles on the surface of the parietal lobe between reliable anatomic landmarks. The apex angles coincide with the intersection point of the dorsal edge of the corpus callosum with the line passing through the most distant points of the ventral edge of the corpus callosum, the sides of the angles cut to the image edge brain level limit the frontal lobe with parietal and occipital it. For data processing analysis of variance (ANOVA) was used.The results showed that the homologous angles did not differ significantly between the sexes. However measurements of length and surface area indicate that are higher in males. It needs to increase the number of cases to obtain reliable values compared with controls and pathological cases. It is concluded that the shape of the region studied in the age range considered, it is similar in both sexes. Variations angle values, regardless of sex, could be clinically useful in the search for signs of psychiatric and / or neurological disorders.
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