Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children

Cleopatra K Mugyenyi,Salenna R. Elliott,Xi Zen Yap,Gaoqian Feng,Philippe Boeuf,Gregory Fegan,Faith Ha Osier,Freya J. I. Fowkes,Marion Avril,Thomas N. Williams,Kevin Marsh,James G. Beeson

Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children

2017

Cleopatra K Mugyenyi
Salenna R. Elliott
Xi Zen Yap
Gaoqian Feng
Philippe Boeuf
Gregory Fegan
Faith Ha Osier
Freya J. I. Fowkes
Marion Avril
Thomas N. Williams
Kevin Marsh
James G. Beeson

Background We investigated the poorly understood impact of declining malaria transmission on maintenance of antibodies to Plasmodium falciparum merozoite antigens and infected erythrocytes (IEs), including functional immunity.

Keywords:

Antibody
Virology
Humoral immunity
Immunity
Immunology
Antigen
Phagocytosis
Medicine
Malaria
Plasmodium falciparum
Transmission (mechanics)
Parasitemia
Acquired immune system

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