Polyostotic fibrous dysplasia: a rare cause of pathological fractures in young patients.

Polyostotic fibrous dysplasia (PFD) is a sporadic benign skeletal condition that typically presents with bone pain, deformities and pathological fractures. It preferentially affects long bones. Sarcomatous transformation, most commonly osteosarcoma, occurs in 7% of patients with PFD.1 Diagnostic challenges exist as radiographic appearances range from cystic foci to pagetoid or sclerotic lesions. Differential diagnoses include juvenile bone cysts, aneurysmal bone cysts and giant cell tumours.2 We describe a case of a 27-year-old woman who had been diagnosed with PFD at the age of 12 years, and who had an extensive history of pathological …