Screening for liver fibrosis in HIV-mono-infected patients with increased ALT comparing FibroScan with FIB-4

Background Elevated ALT values are frequently observed in HIVmono-infected patients. Recent studies have reported cases of cryptogenic liver cirrhosis in HIV+ individuals. Other possible explanations are non-alcoholic/alcoholic steatohepatitis and drug toxicity. We have used two noninvasive methods, liver elastometry (FibroScan) and a serologic fibrosis index (FIB-4), for liver fibrosis screening in a single centre.