The effect of platelet-rich plasma on reducing blood loss after total knee arthroplasty: A systematic review and meta-analysis.

Abbreviations: CI = confidence interval, Development and Evaluation, DVT = deep vein thrombosis, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, Hb = hemoglobin, LOS = length of hospital stay, MD = mean difference, PE = pulmonary embolism, POD = postoperative day, PRP = platelet-rich plasma, RCTs = randomized controlled trials, ROM = range of motion, TKA = total knee arthroplasty, VTE = venous thrombus embolism, WOMAC = Western Ontario and McMaster Osteoarthritis Index. The authors report no conflicts of interest. JM and JS are joint first authors. This study was supported by the Science and Technology Research Fund for the Returned Personnel of Ministry of Human Resources and Social Security of China (No. 2014–QTL–028) and China–Japan Friendship Hospital Youth Science and Technology Excellence Project (No. 2015–QNYC–A–03).