Abstract 15586: GFAT2 Mediates Isoproterenol-Induced Cardiac Hypertrophy by Increasing Protein O-GlcNAcylation and Akt Activation

Background: Cardiac hypertrophy is an independent risk factor for heart failure and cardiac death. The attachment of O-linked N-acetylglucosamine motif (O-GlcNAcylation) to proteins, a post-transla...