KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases

Iris van ‘t Erve,Nina J. Wesdorp,Jamie E. Medina,Leonardo Ferreira,Alessandro Leal,J. Huiskens,Karen Bolhuis,Jan Hein T.M. van Waesberghe,Rutger-Jan Swijnenburg,Daan van den Broek,Victor E. Velculescu,Geert Kazemier,Cornelis J. A. Punt,Gerrit A. Meijer,Remond J.A. Fijneman

KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases

2021

Iris van ‘t Erve
Nina J. Wesdorp
Jamie E. Medina
Leonardo Ferreira
Alessandro Leal
J. Huiskens
Karen Bolhuis
Jan Hein T.M. van Waesberghe
Rutger-Jan Swijnenburg
Daan van den Broek
Victor E. Velculescu
Geert Kazemier
Cornelis J. A. Punt
Gerrit A. Meijer
Remond J.A. Fijneman

PURPOSESomatic KRAS mutations occur in approximately half of the patients with metastatic colorectal cancer (mCRC). Biologic tumor characteristics differ on the basis of the KRAS mutation variant. ...

Keywords:

Colorectal cancer
Cancer research
in patient
KRAS
kras mutation
Medicine

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