Treatment outcomes in patients with toxic megacolon

The aim of the study was to analyze data of patients threated by surgical intervention for toxic megacolon in period from 2005 till 2009 on 1st. dept. of Surgery of 1st. Faculty of Medicine, Charles University in Prague. Pre-disponding illness of toxic megacolon was studied intimately and evaluation of postoperative course especially for morbidity and letality was estimated.Composit retrospective and prospective analysis of patients that underwent operation for diagnose of toxic megacolon. 19 patients were involved in the study and the method of surgical treatment was subtotal colectomy with formation of terminal ileostomy and rectal occlusion in macroscopically disease-free rectal segment in every case.Determined collection involved 19 patients, 13 male and 6 female patients with mean age of 51 years. The most frequent reason for toxic megacolon occurrence was ulcerative colitis (36.8%, 7 patients), then pseudomembranous colitis (26.3%, 5 patients) and ischemic colitis (15.8%, 3 patients). The method of surgical treatment was subtotal colectomy with formation of terminal ileostomy and rectal occlusion in macroscopically disease-free rectal segment in every case.