Abstract 247: Phagocytosis-mediated Activation of Smad3 in Macrophages Mediates Anti-inflammatory Transition and Protects From Adverse Post-infarction Remodeling

Macrophages are essential regulators in tissue injury, repair and fibrosis. Although activation of TGF-β signaling cascades critically modulates macrophage phenotype in vitro, the in vivo role of m...