DDK inhibition disrupts replication leading to mitotic catastrophe in Ewing sarcoma

Jeffrey C Martin,Ajay Gupta,Tamara J Hagoel,Lingqiu Gao,Miranda L. Lynch,Anna Woloszynska,Thomas Melendy,Jeremy Kane,Joseph B. Kuechle,Joyce E. Ohm

DDK inhibition disrupts replication leading to mitotic catastrophe in Ewing sarcoma

2021

Jeffrey C Martin
Ajay Gupta
Tamara J Hagoel
Lingqiu Gao
Miranda L. Lynch
Anna Woloszynska
Thomas Melendy
Jeremy Kane
Joseph B. Kuechle
Joyce E. Ohm

Ewing sarcoma is the second most common bone malignancy in children and adolescents. Patients with upfront metastatic or recurrent disease have poor outcomes with 5-year survival rates of

Keywords:

Malignancy
Cancer research
Mitotic catastrophe
Sarcoma
replication
recurrent disease
Medicine

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