DNA-ploidy as an independent prognostic factor in patients with serous ovarian carcinoma

The knowledge of prognostic factors is of vital importance in patients with ovarian cancer. The established prognostic factors such as the stage of disease, radicality of procedure, tumor grade, patient age, etc., have recently been joined by DNA-ploidy. Some authors believe that aneuŽ . ploidy changed nuclear DNA content represents the main prognostic factor in patients with ovarw x ian carcinoma 1]3 . However, some question its w x independent prognostic significance 4 . In this study we tried to assess the prognostic value of tumor DNA-ploidy in patients with serous ovarian carcinoma. The study included 63 patients with serous