Clinical and Microbiological Efficacy of Continuous Versus Intermittent Administration of Meropenem in Critically Ill Patients

study, was to test for antibacterial activity of a green alga, Caulerpa sertularioides from the Persian Gulf. Methods: The extract from C. sertularioides was prepared by 20minutes boiling of alga in 20% glycerine solution and it was then sterilized using the filteration. A bacterial concentration of 500000 colony forming units (CFU)/ml of Staphylococcus epidermidis (ATCC 14990) as a gram positive or Escherichia coli (ATCC 25922) as a gram negative bacterium were tested with different concentrations of the extract in Mueller-Hinton broth for evaluation of antibacterial effect. Controls without the extract were treated by the same way. Results. The extract showed antibacterial activity against S. epidermidis and E. coli in the concentrations of 34mg/ml and 27.2mg/ml, respectively. Conclusion: C. sertularioides could be a suitable source for isolation of antibacterial compounds and furthert in-vivo investigations.