Tirofiban Rescue in Acute Carotid Stent Thrombosis despite a Standard Antiplatelet Regimen A Case Report

Fifty minutes following implantation of a right internal carotid artery stent, left lower extremity paresis developed in a patient despite use of heparin, clopidogrel and aspirin. Immediate angiograms revealed partially thrombosed carotid stent, then tirofiban (a glycoprotein IIb-IIIa receptor inhibitor) was administered intraarterially into the stent. After 15 minutes, complete resolution of the thrombus was detected on repeat angiography. The patient had recovered completely at 30-day follow-up.