The Polymorphism of IGF-I Gene and its Relationship with some Growth Traits in Saba Pig

The expression products of insulin-like growth factor-Ⅰ(IGF-Ⅰ) gene play an important role in muscle growth of pigs.In this research,IGF-Ⅰ gene was chosen as candidate genes for growth traits of Saba pigs.The HhaⅠ polymorphism of the gene was investigated by using PCR-RFLP technology,and the relationship between the polymorphism and 12 growth traits was analyzed.The results showed that there was a higher degree of polymorphisms on IGF-Ⅰ gene in the population.AA,AB,BB genotypes of IGF-Ⅰ gene were detected in Saba pigs,which frequency were 0.3473,0.5149,0.1378,respectively.The frequency of A and B were 0.6048 and 0.3952,respectively.The gene loci was in Hardy-Weinberg equilibration.The genetic variation of IGF-Ⅰ gene of Saba pigs had significant influence on growth traits(P0.05 or P0.01).The favorable genotype of the body weight and the daily gains at different growth stages was AB genotype,and the favorable genotype of the body size traits at 6 months was BB genotype except partial traits was AB genotype.Combining with the previous results,it could be primarily deduced that IGF-Ⅰ gene was probably a major gene or a QTL linked gene that associated with growth traits in pigs.