Decontamination efficacy of erbium:yttrium–aluminium–garnet and diode laser light on oral Candida albicans isolates of a 5-day in vitro biofilm model

The different forms of superficial and systemic candidiasis are often associated with biofilm formation on surfaces of host tissues or medical devices. The biofilm formation of Candida spp., in general, necessitates signif- icantly increased amounts of antifungal agents for therapy. Often the therapeutic effect is doubtful. A 5-day biofilm model with oral Candida isolates was established according to Chandra et al. (39)(J Dent Res 80:903-908, 2001) on glass and titanium surfaces and was modified by Sennhenn-