Spontaneous rupture of adrenal pheochromocytoma with capsular invasion
2004
A 67-year-old Japanese man developed a sudden onset of severe right-side upper abdominal pain, nausea and vomiting. On hospitalization, physical examination revealed sweating, tachycardia, hypertension and the appearance of peripheral vasoconstriction. An urgent computed tomography scan with contrast demonstrated a large hematoma in the right retroperitoneal space. A phentolamine test and an 131iodine metaiodobenzylguanidine scan suggested pheochromocytoma. An elective right adrenalectomy was successfully performed after pretreatment for sufficient volume replacement with continuous administration of α- and β-adrenergic blocking agents. Pathological diagnosis was an adrenal pheochromocytoma 9.0 × 6.5 cm in diameter with evidence of capsular invasion, which could be associated with a tear in the capsule.
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