Comparison of Whole-Genome Sequencing and Molecular-Epidemiological Techniques for Clostridium difficile Strain Typing

Samuel R. Dominguez, Lydia J. Anderson, Cassandra V. Kotter, Cynthia A. Littlehorn, Lesley E. Arms, Elaine Dowell, James K. Todd, and Daniel N. Frank Department of Pediatric Infectious Diseases, University of Colorado School of Medicine, Aurora; Department of Epidemiology, Children’s Hospital Colorado, Aurora; Department of Adult Infectious Diseases, University of Colorado School of Medicine, Aurora; Department of Pathology and Laboratory Medicine, Children’s Hospital Colorado, Aurora; and Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia