OSTEOGENIC SARCOMA OF THE NASAL CAVITY IN A CAT: POSTOPERATIVE CONTROL WITH HIGH DOSE‐PER‐FRACTION RADIATION THERAPY AND METRONIDAZOLE

An 11-year-old Siamese cat with an osteogenic sarcoma of the nasal cavity was treated by partial surgical excision followed by a course of high dose-per-fraction radiation therapy in conjuction with metronidazole, a hypoxic cell sensitizer. Four thousand two hundred rads were delivered to the tumor in 7 weekly fractions. Each treatment was preceded by 6 gm/m2 oral metronidazole given 3 hours before irradiation. There were no untoward side effects and the cat was in remission 2 years after treatment.