Evaluation of liver volume and its megakaryocyte's population in NMRI mice fetus exposed to electromagnetic field

Background: During the recent decades, a lot of studies were conducted to asses the effect of electromagnetic fields on fetal developmental disorders, sterility, and a variety of neoplasms. The aim of the present study was to determine the effect of low electromagnetic field (LEMF) on the liver’s volume and the number of its megakaryocytes in NMRI mouse fetus. Methods: LEMF of 50 HZ frequency was used and 66 three month old NMRI mouse embryos were divided into 6 groups. The experimental groups were exposed to LEMF and then an embryo was randomly selected from each mother and its liver was extracted and fixed in formalin. Cell counting and volume evaluating were done by stereological methods and the data were analyzed. Results: Although the number of liver megakaryocytes and the embryos weight in all experimental groups as compared to sham and control groups reduced but the differences were not significant. Conclusion: The results of this study revealed that in the pregnant mice exposed to LEMF, irrespective of the length of pregnancy, there was not a significant change in the liver volume and the number of liver's megakaryocytes in NMRI mouse fetus.