Correlation Between Serum Visfatin and Polycystic Ovary Syndrome and Its Clinical Significance

Objective To investigate the correlation between the expression levels of serum visfatin and polycystic ovary syndrome (PCOS) and explore the clinical significance. Methods A total of 65 cases of PCOS inpatients from May 2009 to December 2012 at Tongcheng County People's Hospital of Xianning city as well as 67 cases of physical examinations at outpatient department over the same period were chosen as study subjects.According to body mass index(BMI), they were divided into obese PCOS group (n=32, BMI≥25 kg/m2), non-obese PCOS group(n=33, BMI 0.05). Results The WHR, FINS, HOMA-IR and serum visfatin expression levels of non-obese PCOS group were significantly higher than those of non-obese control group(P 0.05). Conclusions The expression levels of serum visfatin in patients with PCOS has significantly increased compare to healthy individuals and positively correlated with their BMI, which can be used as an auxiliary laboratory indicator for PCOS detection. Key words: Nicotinamide phosphoribosyltransferase; Polycystic ovary syndrome; Body mass index