Serum vitamin D levels in individuals with polycystic ovary syndrome (PCOS), with or without non-alcoholic fatty liver disease (NAFLD).

Nonalcoholic fatty liver disease (NAFLD) has an increasing prevalence in patients with polycystic ovary syndrome (PCOS). Although PCOS is considered as a reproductive disorder, it is also a metabolic disorder due to its involvement in insulin resistance. Obesity and insulin resistance are the main factors related to NAFLD in PCOS. The purpose of this study was to assess NAFLD status in PCOS and analyze vitamin D serum levels in fertile individuals diagnosed with PCOS. A total of 68 female subjects, between the ages of 18 to 38, were recruited to the study. All the subjects were diagnosed with PCOS according to 2003 Rotterdam Revised Consensus by a gynecologist. A questionnaire evaluating general characteristics, physical activity and nutritional habits was administered by a trained dietitian. Abdominal ultrasonography was administered by a radiologist for NAFLD diagnosis. Blood samples were collected. Elecsys® Vitamin D total kits (Roche, Switzerland) were used to analyze the serum vitamin D levels. A tot...