Live Donor Renal Transplant With Simultaneous Bilateral Nephrectomy for Autosomal Dominant Polycystic Kidney Disease Is Feasible and Satisfactory at Long-term Follow-up.

available at http://www.ncbi.nlm.nih.gov/pubmed/26262506 Editorial Comment: This study represents a longer followup of patients with autosomal dominant polycystic kidney disease who underwent bilateral nephrectomy at transplant. This subject was an emerging concept 10 years ago. In this cohort 66 of 118 patients transplanted due to autosomal dominant polycystic kidney disease underwent simultaneous nephrectomy with transplant, which is slightly more than 50% of the cohort. The simultaneous nephrectomy group was compared to a cohort without nephrectomy. Although the operation was longer and involved greater blood loss and a higher rate of complications, patient and graft survival were not different between the 2 groups. Despite a long midline incision, there were no differences between the groups in terms of bowel obstruction or ventral hernia. Patient satisfaction was high with simultaneous nephrectomy. This approach has now become an established alternative to nephrectomy with delayed transplantation and emerges as a patient preference.