Results of QuantiFERON-TB Gold in-tube and skin testing with recombinant proteins CFP-10-ESAT-6 in children and adolescents with TB or latent TB infection

with MMP (n=21) and non-MP pneumonia (n = 20). We selected patients during the same period with bronchial foreign body, airway malformations and chronic cough as the control group (n =20). BALF were collected from all cases at acute phase and recovery phase. The levels of IL-5 and VEGF in BALF and serum were measured by ELISA. All data is statistically analyzed by the application SPSS17.0. Results: 1. The levels of IL-5 and VEGF in BALF and serum in patients with wheeze were higher than those in non-wheeze, non-MP pneumonia group and control group, there was a statistically significant difference of them (P 0.05). Conclusion: IL-5 and VEGF may play important roles in airway inflammation in children with mycoplasma pneumonia and wheeze.