Synthesis and anti-inflammatory activity of gold-nanoparticle bearing a dermatan sulfate disaccharide analog
2018
Abstract A dermatan sulfate (DS) repeating disaccharide analog, α - l -idopyranosiduronate-(1 → 3)-2-amino-2-deoxy-4,6-di- O -sulfo- β - d -galactopyranoside, has been convergently synthesized and successfully applied to prepare the GAG-functionalized gold glyconanoparticle. This new material exhibited good anti-inflammatory activity which was comparable to that of the drug ibuprofen incarrageenan-induced paw edema in a rat model.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
12
References
6
Citations
NaN
KQI