[Relationship between large artery elasticity function and coronary heart disease, lower extremity arterial disease in patients with carotid plaque].

OBJECTIVE: To evaluate the relationship between large artery elastic function and coronary heart disease (CHD) or lower extremity arterial disease (LEAD) in patients with carotid plaque. METHODS: A total of 491 patients with carotid plaque were enrolled into the study with complete data of arterial stiffness detection and blood test [male: 208 and female: 283, and mean age: (61.66±11.60) years]. All the subjects were divided into 2 groups according to CHD or LEAD, namely non-CHDL In the patients with age above 61.66 years, there was no independent association between large artery stiffness and CHD/LEAD (P>0.05). CONCLUSION: The large artery elasticity function in the patients with carotid plaque was poor. In the patients with carotid plaque and higher large artery stiffness below 61.66 years, the risk of the prevalence of CHD/LEAD was increased significantly than with normal arterial stiffness. In the patients with carotid plaque below or above 61.66 years, the independent influencing factors on the prevalence of CHD/LEAD were different.