of relationship between p regnancy induced hypertension and homocysteine

Objective: To assess the homocysteine level in pregnancy induced hypertensive patient and also correlate homocysteine in preeclampsia and pregnancy outcome. Government maternity hospital, Sultan Bazar. 100 subjects were recruited for study during antenatal period irrespective of gesta tional age and gravidae, during the year 2007 who fulfilled inclusion criteria second gravidae. Homocy steine levels are more with patient with second gravidae with diastolic blood pressure more than 100 mm of Hg and also showing significant proteinuria. High homocysteine level with preeclampsia patient have more preterm delivery rate with high caesarean se parameter and coagulopathy. In baby it was with abnormal non stress test. Most of the babies delivered are IUGR, LBW and preterm. Conclusion: Preeclampsia is a leading cause of maternal and mechanism how Hyperhomocysteinemia promotes endothelial dysfunction remains unclear, but it involve both cytotoxic and oxidative stress mechanism to promote endothelial dysfunction in preeclampsia.Hyperhomocysteinem be associated with number of complications in pregnancy. In the form of IUGR, preterm deliveries, low birth weight, repeated abortions, pregnancy induced hypertension and Abruptio placentae. To assess the homocysteine level in pregnancy induced hypertensive patient and also correlate homocysteine in preeclampsia and pregnancy outcome. Method: It is a case control study conducted in antenatal ward at Government maternity hospital, Sultan Bazar. 100 subjects were recruited for study during antenatal period irrespective tional age and gravidae, during the year 2007 -2008, were taken into the study.50 subjects were included those who fulfilled inclusion criteria . Results: Most of the patients are less than 20 years of age. Most of the patient steine levels are more with patient with second gravidae with diastolic blood pressure more than 100 mm of Hg and also showing significant proteinuria. High homocysteine level with preeclampsia patient have more preterm delivery rate with high caesarean se ction rate. It also shows some elevation in liver enzyme, in renal parameter and coagulopathy. In baby it was with abnormal non stress test. Most of the babies delivered are IUGR, LBW Preeclampsia is a leading cause of maternal and fetal mortality and morbidity.The exact mechanism how Hyperhomocysteinemia promotes endothelial dysfunction remains unclear, but it involve both cytotoxic and oxidative stress mechanism to promote endothelial dysfunction in preeclampsia.Hyperhomocysteinem be associated with number of complications in pregnancy. In the form of IUGR, preterm deliveries, low birth weight, repeated abortions, pregnancy induced hypertension and Abruptio placentae. hypertension and homocysteine .