A Mechanism for Cox-2 Inhibitor Anti-Inflammatory Activity in Chemoprevention of Epithelial Cancers

Epidemiological and experimental data support the use of nonsteroidal anti-inflammatory drugs, including specific inhibitors of cyclooxygenase 2 (Cox-2), as chemopreventive agents in a number of epithelial cancers, including colon, mammary, esophageal, lung, and oral cavity [(1)][1] . There is also