Factors Associated with Mortality Outcomes in Neonatal Septicemia in Srinagarind Hospital, Thailand

Background: Neonatal Septicemia is a major cause of mortality and morbidity in newborns both in developed and developing countries. Objective: The objective of this study was to determine the risk factors for mortality in neonatal septicemia Materials and Methods: This retrospective case-control study was conducted in Srinagarind Hospital, Khon Kaen, Thailand. The study considered the demographics, laboratory results, and clinical features for a total of 133 patients during the period May 2005- September 2010. Thirty four out of these patients died from their condition. Results: Investigation of neonatal demographics found that low Apgar scores in 1 minute (OR 12.237, P<0.001) and 5 min (OR 13.143, P<0.001), VLBW (OR 5.312, P<0.001), EOS (3.749, P<0.001), prematurity (2.723, P<0.01), and out born delivery (6.253, P<0.001), were all significantly associated with fatality. Laboratory results showed that hyperglycemia (OR 6.213, P<0.001) and thrombocytopenia (3.853, P<0.002), were significant contributors to fatality. Among all clinical features, lethargy (14.667, P<0.001), apnea (OR 13.160, P<0.001), poor feeding (OR 7.807, P<0.001), hypothermia (OR 4.807, P<0.001) and jaundice (OR4.769

Keywords:

• Acinetobacter
• Jaundice
• Klebsiella
• Infection control
• Lethargy
• Apnea
• Omics
• Pediatrics
• Medicine
• Enterobacter
• Hypothermia

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