Photoelectrochemical impedance spectroscopy sensor for cloxacillin based on tetrabutylammonium octamolybdate

In this study, a sensor based on tetrabutylammonium octamolybdate (Bu4N)4 (Mo8O26) (POM) has been immobilized on the indium tin oxide (ITO) coated glass substrates using the poly(allylamine hydrochloride) (PAH) for a selective determination of cloxacillin. The morphology and the hydrophobicity of the modified electrodes were examined using the scanning electron microscopy (SEM) and contact angle measurements (CAM), respectively. The electrochemical impedance spectroscopy (EIS) is used to follow the detection progress of cloxacillin in the darkness and under illumination with the lowest limits of detection (10–11.5 M) and a wide linear range of 10−11 to 10−7 M. The evolution of the equivalent electrical circuit’s parameters was studied to establish the ability of the light excitation to improve the cloxacillin detection.