Cremaster Chamber Model

In the following study we report on the development and application of the cremaster chamber model. Seventeen male Sprague-Dawley rats were studied in two experimental groups. In the control group, Group I, the muscle flap was preserved in the medial border of the rat’s hind limb. For evaluation the cremaster was removed from the leg and prepared for in vivo observations after 24 h. In Group II, the cremaster muscle chamber was implanted and in vivo observations were performed in post-operative intervals of half an hour, 24, 48 and 72 h, respectively. The study proved that the cremaster chamber model was equal to the classic cremaster muscle preparation for microcirculatory measurements for at least 24 h.