Markers of renal function in patients infected by SARS-CoV-2. quick literature review

Aim Summarize the scientific evidence on kidney disorders associated with SARS-CoV-2 infection Material and methods A rapid review was performed using the Cochrane methodology Results Pre-existing chronic kidney disease (CKD) in patients with SARS-CoV-2 ranged from 1 to 38% and acute kidney injury (AKI) from 2 9 to 86 4% The prognosis of infection was worse in patients with CKD and in those with intact remnant renal reserve (RRR) who developed AKI The risk of death was higher (combined relative risk = 1 49;95% CI: 1 09-2 04) in SARS-CoV-2 infected patients with pre-existing CKD RRR markers showed alterations in patients with severe and fatal SARS-CoV-2;the most widely used marker was serum creatinine Conclusions Scientific evidence shows the relevance of permanent evaluation and monitoring of RRR in patients hospitalized for SARS-CoV-2 to improve the prognosis of those with pre-existing CKD, as well as of those without CKD who develop AKI