First Choice Treatment of Dialysis-Resistant Hypertension: A Crossover Comparison of Single Oral Dose of Captopril and Nifedipine

The proposed stepwise pharmacological treatment of so called “dialysis-resistant” hypertension (DRH), i.e. elevated blood pressure in patients on chronic hemodialysis that is not controlled by ultrafiltration, includes converting enzyme inhibitor Captopril and calcium channel blocker nifedipine as first line drugs (1). The aim of the present study was to compare the acute effects of these drugs in patients with DRH in order to predict the better individual choice.