Abstract 17415: Mitochondrial Ca2+/Calmodulin-Dependent Kinase II Inhibition Changes the Calcium Homeostasis in the Endothelium and Decreases the Vascular Relaxation in Mesenteric Arteries

Celio Damacena De Angelis,Daniel W. Nuno,Olha M. Koval,Kathryn G. Lamping,Isabella M. Grumbach

Abstract 17415: Mitochondrial Ca2+/Calmodulin-Dependent Kinase II Inhibition Changes the Calcium Homeostasis in the Endothelium and Decreases the Vascular Relaxation in Mesenteric Arteries

2020

Celio Damacena De Angelis
Daniel W. Nuno
Olha M. Koval
Kathryn G. Lamping
Isabella M. Grumbach

Introduction: The Ca2+/Calmodulin-dependent Kinase II (CaMKII) is present in mitochondria and cytosol. In mitochondria, it regulates the mitochondrial Ca2+ uptake via the mitochondrial Ca2+ uniport...

Keywords:

Biophysics
relaxation
Kinase
Medicine
Endothelium
Mesenteric arteries
ca2 calmodulin
Calcium metabolism

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