PBRM1 genomic alterations in mesothelioma: Potential predictor of immunotherapy efficacy.

Jeffrey S. Ross,Ethan Sokol,Julia Andrea Elvin,Jo-Anne Vergilio,James Suh,Shakti Ramkissoon,Sugganth Daniel,Eric Allan Severson,Jonathan Keith Killian,Siraj M. Ali,Alexa B. Schrock,Jon Chung,Garrett M. Frampton,Lee A. Albacker,Robert John Corona,Michael Mix,Anna Shapiro,Gennady Bratslavsky,Vincent A. Miller

PBRM1 genomic alterations in mesothelioma: Potential predictor of immunotherapy efficacy.

2018

Jeffrey S. Ross
Ethan Sokol
Julia Andrea Elvin
Jo-Anne Vergilio
James Suh
Shakti Ramkissoon
Sugganth Daniel
Eric Allan Severson
Jonathan Keith Killian
Siraj M. Ali
Alexa B. Schrock
Jon Chung
Garrett M. Frampton
Lee A. Albacker
Robert John Corona
Michael Mix
Anna Shapiro
Gennady Bratslavsky
Vincent A. Miller

8562Background: PBRM1, of the SWI/SNF family, modulates chromatin remodeling. PBRM1 genomic alterations (GA) are enriched in renal cell carcinoma and mesothelioma (MS). Recent evidence suggests tha...

Keywords:

Mesothelioma
Immunotherapy
Cancer research
Pathology
PBRM1
Medicine
Renal cell carcinoma
Chromatin remodeling

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