Molecular biology and immunology

Abstract Objectives: To review basic molecular biology and immunology concepts to provide a foundation for the understanding of current and developing biological treatments for cancer. Data sources: Published scientific papers, review articles, and book chapters. Conclusion: Research into the structure, functions of the human cell, and development of molecular biology techniques, has increased the understanding of cancer pathophysiology. This research has assisted scientists to develop new cancer treatments, collectively called biotherapies. Implications for nursing practice: Oncology nurses are increasingly facing the administration of a variety of new biotherapies. Basic knowledge of molecular biology and immunology will assist the oncology nurse to understand the mechanisms of action of these therapies, leading to improved patient education and more vigilant surveillance of side effects during and after administration.