Capsular Polysaccharide from Klebsiella Pneumonia ATCC 70063: Isolation, Green Synthesis of Silver Nanoparticles and study of Antimicrobial Activity
2016
In modern research, the field of nanotechnology/nanoscience
is the most interesting areas for chemists, biologists/microbiologists for
their commercial demand and it emerges rapidly due to its wide
application in chemistry, electronics ecology, and medicine as well as in
biological fields. Economically preparations of silver nanoparticles using
green synthesis path having biological entities are gradually increase. In
the investigation, synthesis of Ag-nanoparticles were prepared by using
capsular polysaccharide, isolated from Klebsiella pneumoniae ATCC
70063, and characterized by using UV-VIS spectrum band at 437 nm. The
synthesized Ag-nanoparticles were generally found to be very effective as
an antimicrobial agent against some important human pathogens such as
E. coli ATCC 25922, K. pneumonia ATCC 70063, Salmonella typhi MTCC
734 and Salmonella typhimurium ATCC 14028, which are affecting mostly
and causes serious problems to human beings. These Ag-nanoparticles
particle have also sporocidal activity and also responsible for
degradation of bacterial DNA, which may be another reason for
bactericidal activity of the silver nanoparticles.
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