Prevalence of Medication Non-adherence and Associated Factors Among Psychotic Patients in Dessie Referral Hospital, Amhara Region, North East Ethiopia, 2019

Introduction: Psychotic disorders are severe, impairing and typically a chronic mental disorders and the clinical presentations of psychotic symptoms are diverse and affect a person’s thoughts and actions. Therefore, it is psychiatric disorder significantly contribute to the burden of diseases worldwide. Then, non-adherence is a major problem among Psychotic patients. Objective: To assess the prevalence of medication non adherence and associated factors among psychotic patients in psychiatric outpatient department in Dessie Referral Hospital 2019. Methods and materials: A hospitalized based cross sectional study was conducted from October 1/2018 to January 10/2019. The final sample consisted of 395 psychotic patients with on medication were selected by systematic random sampling technique. Morsiky medication adherence rating scale, Birchwood insight scale and oslow social support rating scale were used for data collected. Data was entered, cleaned and stored in EPI info version 3.1 and exported into SPSS version 21 for further analysis. Result: The response rate of the study was 93.6%%. A total of 199 (50.4%) females were participated in this study. The mean age of participants was 37 (SD±14 years) and age ranged from 18 to 88 year. The overall prevalence of medication non -adherence was found to be 44.3%. The factors such as being widowed (AOR=0.324, 95% CI, (0.135-.779), being daily labor (AOR=.344, 95% CI, (.124-.957) and have been suicidal ideation (AOR=0.322, 95% CI, (0.140-0.740) were negatively associated. Whereas being unable to read and write (AOR=2.611, 95% CI, (1.076-6.333) and length of the medication < 6 months (AOR=2.069, 95% CI, (1.127-3.799) were found to be positively associated with medication non-adherence. Conclusion and Recommendation: The result of this study showed that non adherence among psychotic patients was found to be high and indicted independent associated factors. And this finding has significant implications to enhance level of non-adherence by tackling determinant factors (above mentioned in result) and critical intervention program required and further research should be needed.