Outcomes after reduced-intensity conditioning allogeneic HSCT vary by graft type

Use of cryopreserved grafs following reduced-intensity conditioning alloge-neic hematopoietic stem cell transplantation appeared associated with shorter OS and higher rates of graf failure compared with using fresh allografs, according to study results Bankova and colleagues assessed posttransplantation outcomes of 29 patients (median age, 57 years) who underwent allogeneic HSCT with cryo-preserved peripheral blood stem cells from March 2020 to August 2020, who they compared with a control cohort of 60 patients (median age, 61 years;range, 21-71) who received fresh peripheral blood stem cell allogeneic HSCT between March 2019 and August 2020 Results showed signifcantly lower absolute counts of natural killer cells in cryopreserved samples (P = 0159), but they observed no diferences in content of T, B or CD34+ cells or hematopoietic stem cell compartments between graf types