Correlation of Degree of Aortic Valve Stenosis by Doppler Echocardiogram to Quantity of Calcium in the Valve by Electron Beam Tomography

in patients with angina pectoris. 12 Furthermore, our fi ndings raise the important question of whether AS is also associated with NO resistance at a vascular level. In summary, the present study demonstrates that AS, irrespective of the presence and/or absence of CAD, is associated with platelet hyperaggregability and hyporesponsiveness to antiaggregatory effects of NO donor SNP. Treatment with the prophylactic antianginal agent perhexiline improves platelet responsiveness to NO.