Comparison of Efficacy of Pipelle Biopsy with Dilatation and Curettage

Background: To compare efficacy of pipelle biopsy as an office biopsy method with dilatation curettage (D&C) for women referring Ali Ebn e Abitaleb hospital of Zahedan university of medical science in 2015 - 2016. Methods: In this cross sectional study, 200 patients with Abnormal Uterine Bleeding (AUB) who had referred to gynecology clinic of Ali Ebn e Abitaleb Hospital of Zahedan University of medical science, were selected. The patients were randomly allocated to the two groups based on permuted block design method. In 1th group (n = 100), pipelle biopsy was performed as office biopsy and 2th group (n = 100), dilatation curettage (D&C) was performed in operation room. Sampling was done by the same surgeon and was interpreted by the same pathologist. Results: The samples were adequate in 1th group (n = 88), 88% and in 2th group (n = 98) 98%. Fisher test was used for statistical analysis. It reported statistical significant difference between pipelle biopsy and dilatation curettage (D&C) in terms of histopathology and samples efficacy (P = 0.01). Conclusions: Obtained results demonstrated that efficacy of pipelle biopsy is high. Totally this procedure is safe and cost-effective with low complications. However, we should be careful to alternate pipelle biopsy instead of dilatation-curettage (D&C) in AUB approach.