Butorphanol Prevents Morphine-induced Pruritus Without Increasing Pain and Other Side Effects: A Systematic Review of Randomized Controlled Trials

Purpose Pruritus is a frequent adverse event after administration of morphine. Butorphanol has been used to prevent morphine-induced pruritus, but its efficacy is still controversial. The aim of this systematic review was to evaluate the efficacy of using butorphanol to prevent morphine-induced pruritus.