A prospective study tracking longitudinal changes in genome-wide cell-free DNA (cfDNA) methylation to identify early nonresponders to cancer treatment.

Andrew A. Davis,Wade T. Iams,David C. Chan,Michael S. Oh,Robert William Lentz,Rohith Srivas,Nicole J. Lambert,Alex. Robertson,Neil Peterman,Abhik Shah,Timothy G Wilson,J. Close,Peter George,H. Wood,Ayse Tezcan,Ram Yalamanchili,Ken Nesmith,John C. Spinosa,Haluk Tezcan,Young Kwang Chae

A prospective study tracking longitudinal changes in genome-wide cell-free DNA (cfDNA) methylation to identify early nonresponders to cancer treatment.

2019

3042Background: Methylation is an epigenetic modification linked to cancer pathogenesis. The aim was to determine if changes in cfDNA methylation patterns before and after initiation of treatment c...

Keywords:

Genome
Oncology
Prospective cohort study
Methylation
Cell-free fetal DNA
Pathology
Cancer
Medicine
Internal medicine
cancer treatment
cancer pathogenesis
Cancer research
Epigenetics

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