Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer’s disease

Athanasios Metaxas,Marco Anzalone,Ramanan Vaitheeswaran,Sussanne Petersen,Anne M. Landau,Bente Finsen

Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer’s disease

2019

Athanasios Metaxas
Marco Anzalone
Ramanan Vaitheeswaran
Sussanne Petersen
Anne M. Landau
Bente Finsen

Background Discrepant and often contradictory results have accumulated regarding the antidepressant and pro-cognitive effects of serotonin transporter (SERT) antagonists in Alzheimer’s disease.

Keywords:

Amyloid beta
Medicine
Pathology
Familial Alzheimer's disease
Endocrinology
Neuroinflammation
Antidepressant
Serotonin transporter
Disease
Transgenic Model
Internal medicine
Neocortex
Serotonergic
Tumor necrosis factor alpha
DASB
Transgene

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