The role of leukocytes in mechanism of action of balneopeloidotherapy

Treatment with alkaline sulfide mud activates oxidant activity of neutrophils which stimulate body defense and adaptation but can provoke balneoreactions. Lysosomic membranes remain stable as mud does not stimulate phagocytosis. Peloid therapy stimulates a monocytic (macrophagal) lineage of hemopoiesis directed to elimination of intracellular microflora and products of inflammation. Radon therapy depresses oxidant and non-oxidant neutrophil activity thus diminishing damage to tissues and vessels and relieving inflammation.